Marcos S Freire Selected Research

Yellow Fever

1/2018	Plant-Produced Subunit Vaccine Candidates against Yellow Fever Induce Virus Neutralizing Antibodies and Confer Protection against Viral Challenge in Animal Models.
8/2015	An inactivated yellow fever 17DD vaccine cultivated in Vero cell cultures.
4/2013	17DD yellow fever vaccine: a double blind, randomized clinical trial of immunogenicity and safety on a dose-response study.
1/2013	The synergistic effect of combined immunization with a DNA vaccine and chimeric yellow fever/dengue virus leads to strong protection against dengue.
6/2008	Pressure-inactivated yellow fever 17DD virus: implications for vaccine development.
6/2008	Limited replication of yellow fever 17DD and 17D-Dengue recombinant viruses in rhesus monkeys.
10/2007	Construction and characterization of recombinant flaviviruses bearing insertions between E and NS1 genes.
9/2006	Molecular and phenotypic analysis of a working seed lot of yellow fever virus 17DD vaccine strain produced from the secondary seed lot 102/84 with an additional passage in chicken embryos.
1/2006	Expression of foreign protein epitopes at the surface of recombinant yellow fever 17D viruses based on three-dimensional modeling of its envelope protein.
7/2005	Attenuation of recombinant yellow fever 17D viruses expressing foreign protein epitopes at the surface.

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Marcos S Freire Research Topics

Disease

13	Yellow Fever 01/2018 - 01/2002
5	Viremia 10/2020 - 11/2003
5	Infections 01/2018 - 10/2008
5	Dengue (Dengue Fever) 04/2013 - 01/2006
1	Paralysis (Palsy) 01/2011
1	Measles 02/2008
1	Tick-Borne Encephalitis (Encephalitis, Tick Borne) 01/2006
1	Malaria 01/2002

Drug/Important Bio-Agent (IBA)

11	VaccinesIBA 01/2018 - 11/2003
6	Proteins (Proteins, Gene)FDA Link 01/2013 - 07/2005
5	Neutralizing AntibodiesIBA 01/2018 - 11/2003
3	Attenuated VaccinesIBA 08/2015 - 01/2002
3	EpitopesIBA 01/2006 - 01/2002
2	AntibodiesIBA 01/2018 - 04/2013
2	A-Form DNA (A-DNA)IBA 01/2013 - 01/2006
2	RNA-Directed DNA Polymerase (Reverse Transcriptase)IBA 10/2008 - 06/2008
1	RNA (Ribonucleic Acid)IBA 10/2020
1	Subunit VaccinesIBA 01/2018
1	KynurenineIBA 12/2016
1	Tryptophan (L-Tryptophan)FDA Link 12/2016
1	Yellow Fever Vaccine (Vaccine, Yellow Fever)FDA Link 08/2015
1	Dengue VaccinesIBA 01/2013
1	Glycoproteins (Glycoprotein)IBA 01/2013
1	Peptide Hydrolases (Proteases)FDA Link 01/2011
1	DNA VaccinesIBA 01/2011
1	AntigensIBA 01/2011
1	Nucleoside-TriphosphataseIBA 01/2011
1	ChaperoninsIBA 01/2011
1	Immunoglobulin M (IgM)IBA 10/2008
1	Green Fluorescent ProteinsIBA 10/2007
1	Protein Sorting Signals (Signal Peptide)IBA 01/2006
1	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2006
1	IgA receptor (protein B)IBA 01/2002

Therapy/Procedure

1	Art Therapy 02/2016
1	Bioreactors (Bioreactor) 10/2009